Franck Polleux, Labeling of the millions of axons crossing the internal capsule of the mouse embryo

polleux-research-area-ii-slide-2

Labeling of the millions of axons crossing the internal capsule of the mouse embryo. Red:neurofilament 165kD staining. Green: EGFP form the Ngn2 EGFP-KI knockin mice provided by Dr. Francois Guillemot. Horizontal Sections.

Modified from Seibt J1, Schuurmans C, Gradwhol G, Dehay C, Vanderhaeghen P, Guillemot F, Polleux F. Neurogenin2 specifies the connectivity of thalamic neurons by controlling axon responsiveness to intermediate target cues.  Neuron. 2003 Jul 31;39(3):439-52.